DIAG 2735 Hematology - Hematology Hematology Testing...

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Hematology Hematology Testing Coagulation Testing Hematology Tests White cell count White cell differential Red cell count Hematocrit Hemoglobin Indices MCV MCH MCHC Sed. Rate Methemoglobin Iron and TIBC RBC morphology Platelet count Coagulation Tests Bleeding time Prothrombin time INR Activated clotting time Plasma thrombin time Plasma fibrinogen Fibrin split products White Cell Count Total number of WBCs (estimated) Performed by machine 3.9-11.4 thousand/ml Diagnostic for infection, inflammation, or to monitor chemotherapy or radiation therapy Increased = leukocytosis Decreased = leukopenia White Cell Differential Provides % of circulating white blood cells Normal values Neutrophils = 55% Lymphocytes = 35% Monocytes = up to 8% Eosinophils = 1-4% Basophils = 0-1% Neutrophils Increased levels Neutrophilia Leukocytosis Infection (bacterial) Inflammatory disease Decreased levels Neutropenia Marrow depression Aplastic anemia Viral infection Autoimmune disorders Typical Mature Neutrophils: Nucleus separated into lobes (2-5 lobes) with a narrow band of chromatin connecting them 3 lobes is average Twice the size of a rbc Light pink cytoplasm Pink to bluish granules Immature neutrophils: Nucleus has not segmented yet Nucleus is a band Immature Neutrophil Mature Neutrophils Mature Neutrophils Eosinophils Increased levels Allergic reaction Parasitic infection (round worm) flukes, roundworm, nematode, trichenella Skin disease (psoriasis) Neoplastic diseases Low levels Stress Cushing’s Typical Appearance: Banded or bilobed nucleus Granules are uniform size Brick red colour when stained with eosin Basophils Increased levels Chronic myelocytic leukemia (CML) Ulcerative colitis Chronic hypersensitivity (allergy) Granules are histamine and heparin Typical Appearance: Round, indented, band, or lobulated nucleus (usually binucleated) Granules obscure the nucleus Dark granules that vary in size, shape, and colour Least common granulocyte Lymphocytes Increased levels Viral infection Autoimmune disorders Infectious mono
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This note was uploaded on 11/23/2011 for the course DIAG 2735 taught by Professor Josephr.forese during the Winter '11 term at Life Chiropractic College West.

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DIAG 2735 Hematology - Hematology Hematology Testing...

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