DIAG 2735 6 - Hematology Coagulation

DIAG 2735 6 - Hematology Coagulation - Hematology...

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Hematology Hematology Testing Coagulation Testing
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Hematology Tests White cell count White cell differential Red cell count Hematocrit Hemoglobin Indices MCV MCH MCHC Sed. Rate Methemoglobin Iron and TIBC RBC morphology Platelet count
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Coagulation Tests Bleeding time Prothrombin time INR Activated clotting time Plasma thrombin time Plasma fibrinogen Fibrin split products
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White Cell Count page 2 Total number of WBCs (estimated) Performed by machine 3.9-11.4 thousand/ml Diagnostic for infection, inflammation, or to monitor chemotherapy or radiation therapy Increased = leukocytosis Decreased = leukopenia
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White Cell Differential Provides % of circulating white blood cells Normal values Neutrophils = 55% Lymphocytes = 35% Monocytes = up to 8% Eosinophils = 1-4% Basophils = 0-1%
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Neutrophils Increased levels Neutrophilia Leukocytosis Infection (bacterial) Stress Trauma Inflammatory disease Decreased levels Neutropenia Leukopenia Marrow depression Aplastic anemia Megaloblastic anemia Viral infection Autoimmune disorders B vitamin deficiency
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Eosinophils Increased levels Allergic reaction Parasitic infection (worm) flukes, roundworm, nematode, trichenella Skin disease (psoriasis) Leukemia Decreased levels Stress Cushing’s disease
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Basophils Increased levels Chronic myelocytic leukemia (CML) Hodgkins disease Ulcerative colitis Chronic hypersensitivity (allergy) Granules are histamine and heparin Decreased levels Hyperthryroidism Ovulation Pregnancy Stress
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Lymphocytes Increased levels Viral infection Autoimmune disorders Depressed endocrine Infectious mono Lymphatic (lymphocytic) leukemia Decreased levels Chronic debilitating disease Defective lymph circulation High corticosteroid levels
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Monocytes Increased levels TB, hepatitis, malaria, typhoid, leishmaniasis Collagen disorders Subacute bacterial endocarditis Myeloma Monocytic leukemia
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Red Blood Cell Count Main component of blood Helps estimate carrying capacity for oxygen 3.8- 5.1 million/ ml Increased is called polycythemia Decreased is called anemia Production controlled by erythropoetin Erythropoetin levels controlled by oxygen levels in tissues
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DIAG 2735 6 - Hematology Coagulation - Hematology...

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