Chemotherapeutic Drugs-Variant 2

Chemotherapeutic Drugs-Variant 2 - Chemotherapeutic Drugs...

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Variant # 2 1.Which of the following penicillins is broad spectrum in its antimicrobial action and stable in gastric juice: A. Benzylpenicillin B. Phenoxymethylpenicillin C. Ampicillin D. Methicillin E. Ticarcillin 2.The most appropriate way to achieve an effective blood level of penicillin promptly is by: A. An oral dose of phenoxymethylpenicillin B. An intramuscular injection of procaine penicillin C. An intramuscular injection of benzylpenicillin D. In intravenous injection of benzathine penicillin E. An intravenous injection of procaine penicillin 3.Which of the following drugs is NOT used in the management of malaria: A. Doxycycline B. Sulphadoxine C. Streptomycin D. Quinine E. Pyrimethamine 4.All of the following are cell cycle phase specific agents EXCEPT: A. vincristine B. vinblastine C. paclitaxel D. cytosine arabinoside E. cisplatin 5.Which of the following statements concerning cancer chemotherapeutic agents belonging to the class of natural products is true? A. Vincristine and vinblastine have the same mechanisms of action and the same dose-limiting toxicities B. Actinomycin D produces severe cardiomyopathy as a dose-limiting toxicity C. Bleomycin may produce pulmonary fibrosis but is considered to have low bone marrow toxicity D. Doxorubicin and daunorubicin have different mechanisms of action and are used clinically for the same neoplastic diseases 6.Mr. Byron Smythe was taken to the operating room to have thoracic surgery. Following induction of anesthesia with fentanyl and atropine, he was given halothane and succinylcholine. Upon completion of the procedure and discontinuation of anesthesia, Mr. Smythe exhibited apena for nearly two hours requiring him to be maintained on respiratory support. Assuming an iatrogenic basis for the apnea, which of the above is the most likely causative agent for the above reaction: A. fentanyl B. halothane C. succinylcholine D. atropine 7.Rifampin is used mainly in the treatment of: A). cholera B). typhoid fever C). tuberculosis D). rickettsial diseases E). pseudomonas infections 8.Which of the following antitubercular agents is associated with the development of ototoxicity? A). rifampin B). ethambutol C). isoniazid D). streptomycin E). para-aminosalicylic acid 9.Which of the following agents used in the treatment of pulmonary tuberculosis has a toxicity of producing a lupus-like syndrome? A). isoniazid B). rifampin C). ethambutol D). streptomycin E). para-amino salicylic acid 10.Which of the following antitubercular drugs has hyperuricemia as one of its well-documented untoward effects? A). streptomycin
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Chemotherapeutic Drugs-Variant 2 - Chemotherapeutic Drugs...

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