Allergies and Disorders of the Immune Syste1

Allergies and Disorders of the Immune Syste1 - mast cells...

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Allergies and Disorders of the Immune System The immune system can overreact, causing allergies or autoimmune diseases. Likewise, a suppressed, absent, or destroyed immune system can also result in disease and death. Allergies result from immune system hypersensitivity to weak antigens that do not cause an immune response in most people. Allergens , substances that cause allergies, include dust, molds, pollen, cat dander, certain foods, and some medicines (such as penicillin). Up to 10% of the US population suffer from at least one allergy. After exposure to an allergen, some people make IgE antibodies as well as B and T memory cells. Subsequent exposure to the same allergen causes a massive secondary immune response that releases plenty of IgE antibodies. These bind to
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Unformatted text preview: mast cells found usually in connective tissues surrounding blood vessels. Mast cells then release histamine, which starts the inflammatory response. In some individuals the histamine release causes life-threatening anaphylaxis or anaphylactic shock. The immune system usually distinguishes "self" from "nonself". The immune system learns the difference between cells of the body and foreign invaders. Autoimmune diseases result when the immune system attacks and destroys cells and tissues of the body. Juvenile diabetes, Grave's disease, Multiple sclerosis, Systemic lupus erythematosus, and Rheumatoid arthritis are some of the autoimmune diseases....
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