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Unformatted text preview: 3. Dispersive replication involved the breaking of the parental strands during replication, and somehow, a reassembly of molecules that were a mix of old and new fragments on each strand of DNA. The Meselson-Stahl experiment involved the growth of E. coli bacteria on a growth medium containing heavy nitrogen (Nitrogen-15 as opposed to the more common, but lighter molecular weight isotope, Nitrogen-14). The first generation of bacteria was grown on a medium where the sole source of N was Nitrogen-15. The bacteria were then transferred to a medium with light (Nitrogen-14) medium. Watson and Crick had predicted that DNA replication was semi-conservative. If it was, then the DNA produced by bacteria grown on light medium would be intermediate between heavy and light. It was....
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