DNA Replication - polymerases have opened the molecule, an...

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DNA Replication DNA replication involves a great many building blocks, enzymes and a great deal of ATP energy (remember that after the S phase of the cell cycle cells have a G phase to regenerate energy for cell division). Only occurring in a cell once per (cell) generation, DNA replication in humans occurs at a rate of 50 nucleotides per second, 500/second in prokaryotes. Nucleotides have to be assembled and available in the nucleus, along with energy to make bonds between nucleotides. DNA polymerases unzip the helix by breaking the H-bonds between bases. Once the
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Unformatted text preview: polymerases have opened the molecule, an area known as the replication bubble forms (always initiated at a certain set of nucleotides, the origin of replication). New nucleotides are placed in the fork and link to the corresponding parental nucleotide already there (A with T, C with G). Prokaryotes open a single replication bubble, while eukaryotes have multiple bubbles. The entire length of the DNA molecule is replicated as the bubbles meet....
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This note was uploaded on 11/29/2011 for the course BIO BSC1010 taught by Professor Gwenhauner during the Fall '10 term at Broward College.

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DNA Replication - polymerases have opened the molecule, an...

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