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Unformatted text preview: derived from the amino acid tyrosine and are secreted from the thyroid and the adrenal medulla. Solubility of the various hormone classes varies. Synthesis, Storage, and Secretion Steroid hormones are derived from cholesterol by a biochemical reaction series. Defects along this series often lead to hormonal imbalances with serious consequences. Once synthesized, steroid hormones pass into the bloodstream; they are not stored by cells, and the rate of synthesis controls them. Peptide hormones are synthesized as precursor molecules and processed by the endoplasmic reticulum and Golgi where they are stored in secretory granules. When needed, the granules are dumped into the bloodstream. Different hormones can often be made from the same precursor molecule by cleaving it with a different enzyme. Amine hormones (notably epinephrine ) are stored as granules in the cytoplasm until needed....
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- Fall '10