Organic Chemical Evolution The interactions of these molecules would have increased as their concentrations increased. Reactions would have led to the building of larger, more complex molecules. A pre-cellular life would have began with the formation of nucleic acids . Chemicals made by these nucleic acids would have remained in proximity to the nucleic acids. Eventually the pre-cells would have been enclosed in a lipid-protein membrane, which would have resulted in the first cells. Biochemically, living systems are separated from other chemical systems by three things. 1. The capacity for replication from one generation to another. Most organisms today use DNA as the hereditary material, although recent evidence ( ribozymes ) suggests that RNA may have been the first nucleic acid system to have formed. Nobel laureate Walter Gilbert refers to this as the RNA world. 2. The presence of enzymes and other complex molecules essential to the processes needed by living systems. Miller's experiment showed how these
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