Plasmids - genes can be contained on a single R plasmid The R plasmids can be transferred to other bacteria of the same species to viruses and even

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Plasmids , small DNA fragments, are known from almost all bacterial cells. Plasmids carry between 2 and 30 genes. Some seem to have the ability to move in and out of the bacterial chromosome. An episome is a plasmid incorporated in the bacterial chromosome. Plasmids are self- replicating in a manner like the bacterial chromosome. Many plasmids have been recognized for E. coli , including the F plasmids ("sex factors") and R plasmids (drug/antibiotic resistance). The F plasmid contains 25 genes, some of which control the production of F pili (proteins which extend from the surface of F + , or male, cells to the surface of F - , or female, cells).
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The R plasmid conveys drug resistance on cells having it. As many as 10 resistance
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Unformatted text preview: genes can be contained on a single R plasmid. The R plasmids can be transferred to other bacteria of the same species, to viruses, and even to bacteria of different species. Drug (antibiotic) resistance has been found among pathogens causing the diseases typhoid fever, gastroenteritus, plague, undulant fever, meningitis, and gonorrhea. In addition to the more common modes of transfer, R plasmids may be passed through the cell membrane. The resistance genes appear to operate by either breaking down the antibiotics or by circumventing the block the antibiotic places on a key bacterial metabolic pathway....
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This note was uploaded on 11/29/2011 for the course BIO BSC1010 taught by Professor Gwenhauner during the Fall '10 term at Broward College.

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Plasmids - genes can be contained on a single R plasmid The R plasmids can be transferred to other bacteria of the same species to viruses and even

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