Protein Synthesis - New tRNAs bring their amino acids to...

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Protein Synthesis Translation is the process of converting the mRNA codon sequences into an amino acid sequence. Theinitiator codon (AUG) codes for the amino acid N- formylmethionine (f-Met). No transcription occurs without the AUG codon. f-Met is always the first amino acid in a polypeptide chain, although frequently it is removed after translation. The intitator tRNA/mRNA/small ribosomal unit is called the initiation complex. The larger subunit attaches to the initiation complex. After the initiation phase the message gets longer during the elongation phase.
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Unformatted text preview: New tRNAs bring their amino acids to the open binding site on the ribosome/mRNA complex, forming a peptide bond between the amino acids. The complex then shifts along the mRNA to the next triplet, opening the A site. The new tRNA enters at the A site. When the codon in the A site is a termination codon, a releasing factor binds to the site, stopping translation and releasing the ribosomal complex and mRNA. Often many ribosomes will read the same message, a structure known as a polysome forms. In this way a cell may rapidly make many proteins....
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