Lecture_23-Glycolysis_and_TCA

Lecture_23-Glycolysis_and_TCA - How do you deduce a...

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CARBOHYDRATE METABOLISM Glycolysis C: 3 4 How do you deduce a pathway? 1 2 3 4 5 6 1. Find a reagent that inhibits the production of compound 6 E 1 E 2 E 3 E 4 E 5 Example: Compound X inhibits production of compound 6. Concentrations of compounds 1-3 increase. Therefore, compounds 1-3 are used to make 6. They are part of the same metabolic pathway. Where does this inhibitor affect the pathway? A: 1 2 B: 2 3 D: 4 5 E: 5 6 2. Search for a buildup of metabolites. A: 5 B: 4 C: 3 D: 2 E: 1 1 2 3 4 5 6 E 1 E 2 E 3 E 4 + E 5 E 6 7 8 9 10 E 7 E 8 E 9 E 10 -16.7 +1.7 -14.2 +23.8 +7.5 +6.3 -18.8 +4.4 +7.5 -31.4 How many potential control points are there in this pathway? A: 1 B: 1 or 2 C: 2 or 3 D: 3 or 4 E: 4 or 5 1 2 3 4 5 E 1 E 2 E 3 E 4 + E 5 -16.7 +1.7 -14.2 +23.8 +7.5 6 E 6 7 8 9 10 E 7 E 8 E 9 E 10 +6.3 -18.8 +4.4 +7.5 -31.4 How many reactions in this pathway can be driven forward or backward by simply changing reactant and product concentrations?
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pathway. A. anabolic B. catabolic C. amphibolic (both catabolic and anabolic) The glycolytic reactions all occur where in the cell? A. The cytosol B. The mitochondrion C. The ER D. The cytosol and the mitochondrion E. The cytosol and the ER glycolysis 2 phases 10 reactions Phase I: Preparatory Phase II: Payoff (ATP is consumed) (a net gain of ATP) 10 enzymes 11 metabolites all occur in the cytosol a linear pathway enzymes are not physically associated with each other Reaction 1: What type of reaction did hexokinase catalyze? A: oxidation-reduction
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This note was uploaded on 12/04/2011 for the course CHEM 340 taught by Professor T.baird during the Fall '11 term at S.F. State.

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Lecture_23-Glycolysis_and_TCA - How do you deduce a...

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