Exam_3-Key_Fall_2009

Exam_3-Key_Fall_2009 - CHEM 340-Biochemistry I Exam 3-KEY...

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1 CHEM 340-Biochemistry I: Exam 3- KEY November 20, 2009 Part I: Page 1 Page 2 Page 3 1 D 7 B 15 A 2 C 8 C 16 B 3 A 9 C 17 D 4 B 10 A 18 C 5 C 11 B 19 D 6 D 12 D 20 B 13 A 21 B 14 B 22 C Part II: Matching 23) (20 pts.) Lysozyme Chymotrypsin Hydrolyzes glycosidic bonds X Has six sub-sites associated with substrate binding X Is a monomeric enzyme X X One active site residue has an abnormally high pK a X Full activity requires three active site residues X A solvent water molecule is involved in the catalytic mechanism X X Accepted mechanism involves the formation of a transient anionic species X Utilizes transition state stabilization mode of catalysis X X Catalyzes C—O bond breakage in its substrate X Utilizes an acidic amino acid residue in breaking substrate bonds X Accepted mechanism involves the formation of a covalent intermediate X X Potentially capable of destroying itself X Interactions between active site residues is essential for activity X A natural antibiotic X Cleaves C-terminal to aromatic residues X A member of the enzyme family that Dr. Baird’s lab researches X
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2 Part III: True or False . 24) _ F __ Glucose 6-phosphate may be used in synthesis of other sugars or the pentosephosphate pathway, for example. 25)
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This note was uploaded on 12/04/2011 for the course CHEM 340 taught by Professor T.baird during the Fall '11 term at S.F. State.

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Exam_3-Key_Fall_2009 - CHEM 340-Biochemistry I Exam 3-KEY...

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