Biotechnology Matt

Biotechnology Matt - Biotechnology Biotechnology The use of...

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Unformatted text preview: Biotechnology Biotechnology The use of microorganisms, or biological substances, such as enzymes, to perform specific industrial or manufacturing processes Science Fact or Fiction? http://www.flickclip.com/flicks/jurassicpark3.html The process of producing modified DNA in a test tube and reintroducing that DNA into host organisms. Genetic Engineering Synthetic Biology Colonies of the transformed Mycoplasma mycoides bacterium. Image Credit: J. Craig Venter Institute. 1. Gene Therapy (24.5) Dogs with the genetic disease mucopolysaccharidosis VII (MPS VII)- enzyme deficiency leads to clouding of corneas, cardiac disease, bone abnormalities- retroviral vector for neonatal gene therapy Gene therapy No gene therapy http://www.vet.upenn.edu/schoolresources/communications/publications/bellwether/55/gene_therapy.html 2. Transgenic plants (24.2) + = Bacillus thuringiensis corn cry gene Bt-Corn European corn borer 3. Transgenic Animals (24.3) GloFish Assortment + = Zebra fish jellyfish gfp gene 4. Bioremediation Oil-eating bacteria to clean up toxins in the environment Microorganisms are eating creosote and chlorinated phenols in Pensacola, FL http://www.clarkson.edu/news/view.php?id=1095 5. Forensics http://www.king-george.va.us/content6.cfm?cont_uid=2 http://www.guardian.co.uk/science/2007/sep/16/s 6. Pharmaceutical companies http://www.bio.org/speeches/pubs/er/ 7. Research Understanding gene expression, developmental genetics, cancer, aging, genomes, etc. Nearly all labs use some form of biotechnology Tools of the Trade PCR: DNA amplification in vitro Once you know the sequence of part of a gene, you can amplify it P olyermase C hain R eaction Kary Mullis winner of the Nobel Prize in chemistry 11-21...
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Biotechnology Matt - Biotechnology Biotechnology The use of...

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