Congenital and developmental anomalies of the lung

Congenital and developmental anomalies of the lung -...

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ONGENITAL AND CONGENITAL AND EVELOPMENTAL ANOMALIES OF DEVELOPMENTAL ANOMALIES OF THE LUNG Karan Madan Deptt. Of Pulmonary & Critical care Medicine PGIMER handigarh Chandigarh
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eminar outline Seminar outline Introduction Embryology of lung development Classification Individual anomalies
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troduction Introduction Developmental anomalies of the lung are usually detected in the neonatal period and in early childhood. Some are not encountered until later childhood or adulthood. Some can be confused with more sinister abnormalities. An understanding of their imaging features & presentation important for the physician.
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elevant Embryology Relevant Embryology Intrauterine development: Embryonic, pseudoglandular, canalicular & saccular (alveolar). 26th day gestation - Ventral diverticulum of the foregut ext 2 days, the right and left lung buds arise from this Next 2 days, the right and left lung buds arise from this outpouching Respiratory portion of the gut becomes separated from the esophageal portion by tracheoesophageal septum. Lung buds elongate into primary lung sacs & the 5 lobar bronchi appear.( Upto 5th week – Embryonic phase)
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elevant Embryology Relevant Embryology lobar bronchi branch in a dichotomous fashion 5 lobar bronchi branch in a dichotomous fashion By 16 th week, virtually all of the conducting airways are present. irways are blind tubules lined by columnar or uboidal pithelium Airways are blind tubules lined by columnar or cuboidal epithelium – Pseudoglandular (5 -16 th week) analicular eriod (17th to 25th 8th weeks) Canalicular period (17th to 25th–28th weeks) Saccular (alveolar) period – Alveoli demonstrated as early as 30 weeks gestation. Final period of normal intrauterine lung development from 36 weeks to term - Prolific development of alveoli. Postnatal period - Alveolar development continues
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CLASSIFICATION RONCHOPULMONARY OMBINED LUNG & ASCULAR BRONCHOPULMONARY (LUNG BUD) ANOMALIES COMBINED LUNG & VASCULAR ANOMALIES VASCULAR ANOMALIES A. Congenital bronchial atresia B. Congenital lobar A. Hypogenetic lung (scimitar) syndrome B. Bronchopulmonary A. Absence of a main pulmonary artery B. Anomalous origin of the emphysema C. Congenital cystic adenomatoid malformation sequestration, both intralobar and extralobar left pulmonary artery from the right C. Anomalous pulmonary enous drainage (partial or D. Pulmonary bronchogenic cysts (BPFM) racheal bronchus venous drainage (partial or complete) D. Pulmonary arteriovenous alformation E. Tracheal bronchus F. Accessory cardiac bronchus malformation G. Tracheomalacia H. Tracheal stenosis I. Pulmonary underdevelopment
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ronchial tresia Bronchial atresia Focal obliteration of a proximal segmental or subsegmental bronchus. Lacks communication with the central airways evelopment of distal structures is normal. Development of distal structures is normal.
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Congenital and developmental anomalies of the lung -...

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