BIOL 430 2010 lecture 11 handout 6 slides

BIOL 430 2010 lecture 11 handout 6 slides - Drosophila...

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1 BIOL 430 Lecture 11 February 3 rd 2010 Development of the Drosophila body plan Maternal genes BIOL 430 Molecular Genetics of Development 2010 Dr. Ian Chin-Sang (www.chin-sang.ca) A-P and D-V patterning Drosophila melanogaster BIOL 430 Molecular Genetics of Development 2010 Dr. Ian Chin-Sang (www.chin-sang.ca) Fig. 2.7 All these examples are transcription factors Specifying the A-P axis Fig. 2.8 BIOL 430 Molecular Genetics of Development 2010 Dr. Ian Chin-Sang (www.chin-sang.ca) See end of Chapter 2 (Wolpert) for a summary table of all the genes we will discuss. Clever names: http://tinman.nikunnakki.info/?q=by_organism Maternal A-P genes BIOL 430 Molecular Genetics of Development 2010 Dr. Ian Chin-Sang (www.chin-sang.ca) regions affected Fig. 2.9 Maternal effect genes ( meg) +/ meg X +/ meg 50% (+/ meg) 25% ( meg/meg) 25% (+/+) (Alive!) 50% and Maternal Rescue Alive eg. bicoid BIOL 430 Molecular Genetics of Development 2010 Dr. Ian Chin-Sang (www.chin-sang.ca) meg/meg X +/meg +/meg meg/meg (Dead) (Dead! strict maternal effect) 50% and Maternal effect lethality The anterior cytoplasm is necessary and sufficient for anterior structures bcd mutant no head two “tails” BIOL 430 Molecular Genetics of Development 2010 Dr. Ian Chin-Sang (www.chin-sang.ca) Fig. 2.10
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2 mRNA BIOL 430 Molecular Genetics of Development 2010 Dr. Ian Chin-Sang (www.chin-sang.ca)
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This note was uploaded on 12/06/2011 for the course BIOL 430 taught by Professor Dr.ianchin-sang during the Winter '10 term at Queens University.

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BIOL 430 2010 lecture 11 handout 6 slides - Drosophila...

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