335-11 lec5.ppt

335-11 lec5.ppt - Hodgkin Huxley During an action potential...

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During an action potential, - changes in membrane permeability to specific ions; - distinct, voltage-dependent conductances for Na+ and K+. .. voltage-gated Na+ and K+ channels Na+ Na+ K+ K+
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Pre-Lab Activity What defines the ‘driving force’? {E and V are the same…} a. Vcommand - Imembrane b. Vmembrane - ENernst c. Imembrane - Vmembrane d. ENernst - Vmembrane
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Pre-Lab Activity What defines the ‘driving force’? {E and V are the same…} a. Vcommand - Imembrane b. Vmembrane - ENernst c. Imembrane - Vmembrane d. ENernst - Vmembrane Na+ Na+ K+ K+ i = γ * (Vm - ENernst )
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Pre-Lab Activity What is Popen? a. Probability that action potential fires… b. Probability that an ion channel is closed… c. Probability that threshold is reached… d. Probability that an ion channel is open…
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Pre-Lab Activity What is Popen? a. Probability that action potential fires… b. Probability that an ion channel is closed… c. Probability that threshold is reached… d. Probability that an ion channel is open… open closed
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Defining Membrane Conductances in Squid Axon…
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1. Cleverly used a technique…voltage clamp… 2. 3. Hypothesized that changes in membrane conductance was due to ion channels but other alternatives were also considered. 4.
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This note was uploaded on 12/06/2011 for the course BIO 335 taught by Professor Cabot during the Fall '08 term at SUNY Stony Brook.

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335-11 lec5.ppt - Hodgkin Huxley During an action potential...

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