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Unformatted text preview: women o The malignant cells invade deeper tissues but typically spread out horizontally first Nodular o Often appear as a nodule on the skin which bleed o More commonly found on the chest and back o This form of melanoma spreads only into the deep tissues and the risk of spread to distant organs is high Acral o These appear on the palms of the hands and soles of the feet; often near the nail beds where there may be discolouration Lentigo maligna o Typically present as dark brown flat sub-cuticular patches of the faces of sun-damaged elderly people o They may spread after years of dormancy Causes Malignant melanoma is usually caused by UV exposure, either from direct sun exposure or Sun-beds. Due to the dark pigmentation of melanocytes they absorb more UV light and as such their DNA can become damaged. Other risk factors include:- Fair skin light skinned people are at the highest risk of melanoma Sunburn sustained in childhood High number of moles...
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- Fall '10