PsoriasisSymptoms - Variants of psoriasis include •...

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Psoriasis Symptoms Scaly plaques (elbows, knees, and/or extensor surfaces, scalp) Guttate psoriasis = widespread scaly papules in the distribution of water droplets on trunk, arms, and legs (often after an upper respiratory infection) Pruritis Starts with 1 or 2 lesions (elbows or scalp) --- spreads to trunk Painful skin and/or joints Risk Factors = Stress, Trauma, Smoking, Light skin colour Causes Psoriatic plaques are hyperproliferative and show infiltration of T-cells. 3 contributing factors Infection = cause guttate Genetics = FHx with HLA link Immunology = aggravated by lithium and beta-blockers Note: The silver scale on the surface of lesions = layer of dead cells
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Unformatted text preview: Variants of psoriasis include: • Guttate psoriasis – numerous smaller plaques spread over the body • Flexural psoriasis – affecting the axillae, perineal creases and other flexures. • Nail psoriasis – common, and characterised by pitting in the nails, onycholysis, thickening and crumbling, splinter haemorrhages and subungal hyperkeratosis • Brittle / confluent psoriasis – merging, widespread areas • Other = Pustular psoriasis, Palmoplantar pustulosis Epidemiology o mean age of onset = 28 years o equal distribution between men and women o 7-11% have psoratic arthritis....
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This note was uploaded on 12/04/2011 for the course ANT ANT2000 taught by Professor Monicaoyola during the Fall '10 term at Broward College.

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PsoriasisSymptoms - Variants of psoriasis include •...

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