Basal cell carcinoma Diagnosi1

Basal cell carcinoma Diagnosi1 - • Surgical resection o...

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Basal cell carcinoma Diagnosis A patient presenting with a BCC will usually have a reasonable, yet significant history of sun/UV exposure. There is also often signs of longstanding sun-damaged skin. The physician needs to elicit a thorough whole-body examination on all patients presenting with skin lesions to look for other signs of malignant skin changes. Although there may be clinical suspicion of BCC, the diagnosis of a cancer is histological. Therefore, all lesions must be biopsied or surgically removed and examined under microscopy. The histopathological features of a BCC will show dermal masses of varying sizes and shapes. These cells typically have large oval and uniform nuclei, with little cytoplasm. Treatment There is no significant rush to treat BCC’s like other malignant cancers, as they are usually slow growing and have little metastatic potential. However, BCC should not be treated conservatively and removal of the lesion is required. Typical treatment will involve:
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Unformatted text preview: • Surgical resection o Curettage o Electrodessication o Radiotherapy • Topical Therapy o Cryosurgery (not a traditional topical agent – for local destruction) o 5-fluoruracil o Imiquimod • Other o Phototherapy o Radiotherapy o Prognosis After surgical treatment there may be a visible scar. However, the recurrence rate is typically less than 3%. Topical therapy will not leave as drastic of a scar, but this method of treatment will usually have a much higher recurrence rate. Patients with BCC’s have a significantly higher risk of developing a second BCC and should be followed up regularly for new lesions. In addition, monthly self-screening with another person (such as a spouse) is highly recommended. Prevention The main preventative measure is to avoid excessive sun exposure. Other preventative measures include avoiding x-rays, and arsenic. Patients should be educated on the importance of sunscreen use and other protective garments when out in sun....
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This note was uploaded on 12/04/2011 for the course ANT ANT2000 taught by Professor Monicaoyola during the Fall '10 term at Broward College.

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Basal cell carcinoma Diagnosi1 - • Surgical resection o...

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