Acromegaly - Acromegaly .back Acromegaly is a chronic and...

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Acromegaly «...back Acromegaly is a chronic and multi-systemic disease associated with excessive secretion of Growth Hormone. Symptoms The symptoms of acromegaly are often non-specific and so gradual, that many patients are unaware that there is a medical diagnosis. This explains why when a diagnosis is finally made, it is often up to 10 years after the onset of the disease. Common symptoms of the disease include: Facial coarsening = increased frontal bossing, enlarged nose and jaw Thickened skin and soft tissue (increased risk of carpal tunnel syndrome) Joint pain (increased risk of osetoarthritis) Snoring Symptoms of diabetes (due to insulin resistance from excessive GH +/- IGF-1) Symptoms of hypertension (due to hypertrophy in the arterial muscle layer) Causes Acromegaly is due to excessive secretion of Growth Hormone (GH). This is most commonly due to a pituitary somatotroph adenoma, but in very rare cases may be due to a neuroendocrine tumour that secretes excessive amount of GH-releasing hormone (GHRH). Professional and amateur body builders
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Acromegaly - Acromegaly .back Acromegaly is a chronic and...

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