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Unformatted text preview: 2. Treat the underlying cause Central: 1. Give parenteral or oral DDAVP (analogue of AVP) such as desmopressin 2. Regular monitoring of serum sodium and urine and serum osmolality to prevent dehydration Peripheral: 1. Maintains an adequate fluid intake 2. Low-sodium diet (<500 mg/day), thiazide diuretics can also be tried with the hope of reducing urinary output. Prognosis Usually cases of central DI are transient and resolve or over a matter of months. In patients with peripheral DI as a result of medications, the DI may be irreversible; although it would not be uncommon for it to resolve after discontinuation. Ultimately, it is a watch-and-wait process. Prevention Monitoring renal and urine output is important for patients taking medications known to induce DI....
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- Fall '10