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Hypothyroidism Epidemiology

Hypothyroidism Epidemiology - Hypothyroidism Epidemiology...

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Hypothyroidism Epidemiology Incidence in the UK = 0.41% /yr women ; 0.06%/yr men Diagnosis The only validated test to diagnose primary hypothyroidism, is to measure thyroid-stimulating hormone (TSH) and free thyroxine (T4). However, these levels can be affected by non-thyroidal illnesses. High levels of TSH indicate that the thyroid is not producing sufficient levels of thyroid hormone (mainly as thyroxine (T4) and smaller amounts of triiodothyronine (T3)). However, measuring just TSH fails to diagnose secondary and tertiary hypothyroidism, thus leading to the following suggested blood testing if the TSH is normal and hypothyroidism is still suspected: Free triiodothyronine (fT3) Free levothyroxine (fT4) Total T3 Total T4 Additionally, the following measurements may be needed: Free T3 from 24-hour urine catch Antithyroid antibodies — for evidence of autoimmune diseases that may be damaging the thyroid gland Serum cholesterol — which may be elevated in hypothyroidism
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