Multiple endocrine neoplasia

Multiple endocrine neoplasia - Note Primary...

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Multiple endocrine neoplasia Multiple endocrine neoplasia syndromes (MEN) are a group of hereditary tumour syndromes that are characterised by specific symptoms and tumour locations. Summary Classification Multiple endocrine neoplasia syndromes (MEN1 and MEN2A/ B) are a group of tumours that typically arise from neuroendocrine cells. They are classified based on common symptoms and location of lesions in the body. MEN1: (think of the 3 P’s) Parathyroid adenomas Pituitary adenomas Pancreatic tumours or other gastromas
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Unformatted text preview: Note: Primary hyperparathyroidism will be commonly associated with MEN1. MEN2 There are different subgroups of MEN2, most commonly MEN2A, MEN2B MEN2A: • Medullary thyroid cancer • Phaeochromocytoma • Parathyroid adenomas with symptoms of hyperparathyroidism May also be associated with Hirschsprung's disease and cutaneous lichen amyloidosis. MEN2B: • Medullary thyroid cancer • Phaeochromocytoma (serum levels of vanillylmandelic acid are increased) • Mucosal intestinal tumours...
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This note was uploaded on 12/04/2011 for the course ANT ANT2000 taught by Professor Monicaoyola during the Fall '10 term at Broward College.

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Multiple endocrine neoplasia - Note Primary...

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