Biology 1201

Biology 1201 - Eucaryotic Gene Regulation Genome Structure...

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Biology 1201 October 17, 2011 How does DNA contain information? What is this information used for ? How is this regulated? Bacterial Genome Organization Single circular chromosome Naked DNA No Introns Located in the cytoplasm Plasmids Do the differences in organization lead to functional differences? Transcription and translation can occur simultanesouly Easy for the cells to take up foreign DNA Gene Regulation Why regulate? Energetics Control Bacterial Operon Promoter Operator Structural Genes Regulator produces repressor Repressible Operon Trp Operon Repressor produced in an inactive form Binds with co-repressor Complex blocks transcription Inducible Operon Lac Operon Repressor produced in an active form Blocks transcription Positive Gene Regulation cAMP cAMP Receptor Protein (CRP)
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Unformatted text preview: Eucaryotic Gene Regulation Genome Structure, Genes, DNA, and chromosomes Complete Genome DNA sequence know humans ,chimps ,flies ,worms, and plants… Each chromosome is a one DNA Molecule 22,000 Genes- Humans (14,000 in flies) Human Genome Genes are at set positions on the chromosomes-5000 expressed in each cell type-1000 “ housekeeping” genes Clicker Question Which of the following can describe the way eukaryotic genes are distributed among the chromosomes?-Randomly There are 22,000 human genes in the genome. How many different kinds of preteins can be produced from theses genes?-millions, tens of thousands Eucaryotic Gene Regulation-prokaryotic gene regulation occurs at the level of...
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Biology 1201 - Eucaryotic Gene Regulation Genome Structure...

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