Milestones%20in%20Molecular%20Genetics - Milestones in...

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Unformatted text preview: Milestones in Molecular Genetics Avery, MacLeod and McCarty (1944, in Experimental Medicine, vol. 79). Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Beginning with Griffeths studies of transformation of rough Pneumococcus into smooth, Avery, MacLeod and McCarty demonstrated that the transforming principle was DNA, not protein. Hershey and Chase (1952, in Journal of General Physiology, vol 36(1)). Independent functions of viral protein and nucleic acids in growth of bacteriophage. Using bacterial viruses, Hershey and Chase demonstrated that the infectious portion of a virus is its DNA, not its protein. Chargaff (1950, in Experimentia, vol. 6). Chemical structural specificity of nucleic acids and mechanism of their enzymatic degredation. Chargaff showed that all DNA molecules contained equal numbers of adenine and thymine bearing degredation....
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This note was uploaded on 12/06/2011 for the course BIO 101 taught by Professor Lynnj.fancher during the Spring '05 term at College of DuPage.

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