nobelprize

nobelprize - 2006 Nobel Prize in Chemistry"for his studies...

Info iconThis preview shows pages 1–18. Sign up to view the full content.

View Full Document Right Arrow Icon
2006 Nobel Prize in Chemistry Prof. Roger Kornberg Dept. of Structural Biology Stanford University "for his studies of the molecular basis of eukaryotic transcription"
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
2 Dr. Kornberg
Background image of page 2
3 Heterocycles in DNA and RNA N N N N NH 2 H N N N N O H H NH 2 N N NH 2 O H N N O H O H 3 C H Guanine Thymine Cytosine Adenine N N O H O H Uracil
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
4 Nucleotides The DNA/RNA bases are attached to phosphosugars
Background image of page 4
5 Nucleic Acid Structure The nucleotides are connected together by the phosphates on the sugars
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
6 DNA Structure 1953 - Watson and Crick discovered DNA was made up of two strands running in opposite directions The strands are held together by hydrogen bonding from the bases Specific bases bind to each other like lock and key The strands are Complementary
Background image of page 6
7 Bases Pair up with Hydrogen Bonds Guanosine matches with Cytosine Adenine matches with Thymine
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
8 DNA Double Helix Two grooves are formed Sugar phosphate runs along the outside The major groove is slightly bigger and deeper than the minor groove
Background image of page 8
9 The Genes DNA is a code for the synthesis of proteins. Every 3 base pair sequence is directly correlated with a specific amino acid.
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
10 Transcription DNA unwinds and codes an RNA strand RNA Polymerase
Background image of page 10
11 Translation RNA encodes the amino acid sequence for protein synthesis
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
12 Observed at the molecular level
Background image of page 12
x-ray crystallography to see the action 13
Background image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
14 Dr. Kornberg
Background image of page 14
DNA Wraps Around Histone Proteins 15
Background image of page 15

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Nucleosomes Coil Up 16
Background image of page 16
Wrapped Up Tight 17
Background image of page 17

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 18
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page1 / 29

nobelprize - 2006 Nobel Prize in Chemistry"for his studies...

This preview shows document pages 1 - 18. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online