Major Points, Lecture 15 SS10

Major Points, Lecture 15 SS10 - 17 What is fundamental...

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BSCI105, Freshman Connection Fall 2010 Major Points, Lecture 15 (Chapter 17) 1. Define the "Central Dogma of Molecular Biology." 2. What are some additional processes that complicate the central dogma? 3. How are the processes involved in gene expression and protein production organized spatially in the cell? 4. What are three kinds of information found in genes that are required for transcription? 5. Does RNA have roles other than making peptides? 6. How are genes organized along chromosomes? 7. Define "upstream" and "downstream" directions of a gene. 8. Define transcription. 9. What enzyme makes RNA? 10. What is the "template strand?" 11. What is the "coding strand?" 12. What other enzymatic activity does RNA polymerase have besides linking nucleotides? 13. What are three RNA polymerases in eukaryotes? What are their functions? 14. What determines which ribonucleotides are used in an RNA sequence?
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15. Define the four phases of transcription. 16. What promoter element recruits RNA polymerase during initiation of transcription?
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Unformatted text preview: 17. What is fundamental difference in the requirements for RNA ploymerase to bind DNA in prokaryotes and eukaryotes? 18. In eukaryotes, what is the function of TATA binding proteins? 19. Contrast "basal" transcription factors with "specific" or "regulatory" transcription factors. 20. What are the elements involved in the formation of the transcription initiation complex? 21. What happens during the elongation phase of transcription? 22. Compare termination in prokaryotes and eukaryotes. 23. Contrast the role of RNA processing in prokaryotes and eukaryotes. 24. Draw a typical mRNA, showing/labeling the major elements. 25. What is the structure and function of a 5' Cap on mRNA? 26. What is the structure and function of a 3' polyA tail? 27. Describe what happens during pre-mRNA splicing. 28. Where does splicing occur? 29. What protein complex performs mRNA splicing? 30. What are the steps involved in splicing?...
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This note was uploaded on 12/08/2011 for the course BSCI 105 taught by Professor Jensen during the Summer '07 term at Maryland.

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Major Points, Lecture 15 SS10 - 17 What is fundamental...

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