StudyGuide4 SS10

StudyGuide4 SS10 - BSCI105, Section 0111 Summer 2010 Study...

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Summer 2010 Study Guide #4 I. Cell Communication Vocabulary: Transduction Autocrine Paracrine Endocrine Synaptic Hormone Ligand Receptor G-protein Kinase Second messenger cAMP Adenylyl cyclase DAG IP3 PIP2 Phoshpholipase C Dimer Cascade Phosphorylation Dephosphorylation Key Concept 1: Unicellular organisms communicate to influence the behavior of other cells and mediate cooperative activities such as mating (conjugation) or aggregation. Key Concept 2: Multicellular organisms depend on cellular communication to coordinate numerous processes such as cell division, metabolic regulation, organ size determination, reproduction, and many others. Key Concept 3: Cellular signaling is a basic process involving transmission of a signal by a sending cell and reception of and response to the signal by one or more receiving cells. Key Concept 4: Local signaling through direct contact or secreted molecules influences the signaling cells own behavior (autocrine), or the behavior of neighboring cells (paracrine). Key Concept 5: A special case of local signaling is synaptic signaling, which involves close interactions within a network of cells such as the nervous system. Key Concept 6: Long-distance endocrine signaling by hormones regulates and coordinates the activity of distant cells within the body. Key Concept 7: The receipt of a signal involves three stages: reception, mediated by receptors, signal transduction, mediated by enzymes, and a response either through a change in cell behavior or gene expression. Key Concept 8: Any kind of molecule can act as a ligand for a cellular receptor, but all ligands are share a small number of different receptor types: the transmembrane G- protein coupled receptors, receptor tyrosine kinase, and gated ion channels, and the intracellular nuclear hormone receptors. Key Concept 9: Gated ion channels open when bound by ligand, allowing solutes to diffuse
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This note was uploaded on 12/08/2011 for the course BSCI 105 taught by Professor Jensen during the Summer '07 term at Maryland.

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StudyGuide4 SS10 - BSCI105, Section 0111 Summer 2010 Study...

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