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Study Guide, Chapter 16b

Study Guide, Chapter 16b - BSCI105 Freshman Connection Fall...

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BSCI105, Freshman Connection Fall 2010 Study Guide #12 I. DNA Replication Vocabulary: Replication Semiconservative Conservative Dispersive Meselson & Stahl Circular chromosome Linear chromosome Histone Nucleosome Origin Replication fork Helicase Single-strand binding protein (SSBP) Topoisomerase Primase Polymerase Primer Leading strand Lagging strand Continuous Discontinuous Okazaki fragment Ligase Telomeres Key Concept 1: DNA structure provides a simple means of replication through strict base paring and synthesis of new strands using old strands as templates. Key Concept 2: Meselsen & Stahl conclusively demonstrated that DNA replication is semi- conservative, as opposed to strictly conservative or dispersive. Key Concept 3: Prokaryotes have relatively small genomes with a single circular chromosome, while eukaryotes have large genomes with many linear chromosomes. Key Concept 4: DNA in chromosomes is wound around Histone-protein complexes called nucleosomes.
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