16rna2 - Lecture 16: Translation Chapter 21: Gene...

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Unformatted text preview: Lecture 16: Translation Chapter 21: Gene Expression The Big Picture Finally making a protein ! Roles of rRNA , tRNA , and amino acids How do we regulate DNA/RNA/protein expression? Key Players in Gene Expression DNA mRNA rRNA tRNA Amino Acids Protein Steps of Gene Expression 1.) Transcription 2.) Translation Converting genetic information from mRNA nucleotides into a protein Translation Overview Second step in gene expression Translation: convert a message from one language to another Turn mRNA codons into amino acids Translation Location In eukaryotes , on the rough endoplasmic reticulum Ribosomes studded on surface rRNA Non-coding RNA Combines with protein to make ribosomes Site of protein synthesis tRNA Non-coding RNA One end: reads mRNA One end: carries amino acid Steps of Translation 3 Steps of Translation: 1.) Initiation 2.) Elongation 3.) Termination 1.) Initiation mRNA binds to small ribosomal subunit Then the first tRNA and large subunit associate Ribosomes not fully constructed until translation needs to take place mRNA tRN A a.a. Ribosome Binding Sites...
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16rna2 - Lecture 16: Translation Chapter 21: Gene...

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