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PathophysiologyCellular injury due to the lack of oxygen---prolonged ischemia. Coronary occlusion results in cell death distal to the occlusion (narrowing of epicardial blood vessels due to plaque). Damaged cells cause decreasedmyocardial contractility resulting in decreased stroke volume, cardiac output, blood pressure, and tissue perfusion decreased contractility, LV compliance, stroke volume, and ejection fraction.MedicationsMorphine to reduce pain and anxiety, ACE inhibitors to decrease blood pressure and oxygen demand,and thrombolytics to allow blood flow through the coronary artery. Nursing InterventionsOxygen administrations, encouragement of bed rest, encouragement of changing if positions, checking skin temperature and peripheral pulses, provide truthful information, and monitoring the patient closely for changes in cardiac rate and rhythm, heart sounds, blood pressure, etc. Medical DiagnosisMyocardial InfarctionLabs and Diagnostic Testing12-lead ECG, Blood studies (biochemical markers), echocardiogram, and cardiac