topic25 - BIOL 1030 TOPIC 25 LECTURE NOTES Topic 25:...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
BIOL 1030 – TOPIC 25 LECTURE NOTES Topic 25: Endocrine System (Ch. 45) I. function A. coordination and regulation of body functions B. via regulatory molecules (chemical signals are easy to send in the bloodstream and can have target specificity) II. types of regulatory molecules A. neurotransmitters (wait for nervous system) B. hormones – secreted by endocrine glands, carried in blood, only target cells respond C. autocrine regulators – not transported in blood, acts within an organ on cells similar to the secretory cells D. paracrine regulators – same as autocrine, but acts on cells of a different tissue type from secretory cells E. pheromones affect other individuals of the same species; often used for sexual attraction or signaling, but also for control; typically produced by exocrine glands F. there is some overlap; definition based on how transported and used, not chemical identity III. autocrine and paracrine regulation A. many types B. common autocrine: cytokines in immune system (actually travel in the blood) C. paracrine examples 1. growth factors (stimulate cell division and proliferation) 2. prostaglandins modified lipids many functions, including promoting pain and fever in inflammation and stimulating smooth muscle contraction NSAIDS inhibit (includes aspirin) by inhibiting making of prostaglandins IV. how hormones work A. lipid-soluble hormones enter target cells 1. includes steroid hormones and thyroxine 2. travel in blood attached to protein carriers 3. steroids derived from cholesterol bind to receptor proteins in the cytoplasm or nucleus of the target cell complex binds to specific DNA region, activating or enhancing gene transcription examples: cortisone, testosterone, estrogen, progesterone
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 12/05/2011 for the course BIOL 1030 taught by Professor Folkerts during the Fall '07 term at Auburn University.

Page1 / 3

topic25 - BIOL 1030 TOPIC 25 LECTURE NOTES Topic 25:...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online