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Unformatted text preview: 1. Decreased red-cell life span (haemolytic) 2. Blood loss 3. Congenital defect (sickle cell, hereditary spherocytosis) 4. Acquired (malaria, some drugs) 5. Impairment of red-cell formation 6. Insufficient erythropoiesis 7. Haematinic insufficiency (iron, folate, B12, protein) 8. Chronic disease (infection, renal, liver, collagen) 9. Endocrine deficiency (hypo T4, hypotestes, hypoanterior pituitary) 10. Myelotoxic agents 11. Ineffective erythropoiesis 12. Marrow infiltration (carcinoma, myeloma, leukaemia, lymphoma, myelofibrosis, lysosomal storage disease 13. Miscellaneous (non-haematinic deficiency megaloblastic anemias, myelodysplastic syndromes, malaria) 14. Pooling and destruction of red cells in enlarged spleen 15. Increased plasma volume 16. Reticulocyte count low or normal (rr 0.5 – 2.0%) in impaired erythropoieses...
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- Fall '10
- Anthropology, red cell count, packed cell volume, Anaemia Anaemia