Antibiotics Glycopeptides

Antibiotics Glycopeptides - Loop diuretics increased...

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Antibiotics Glycopeptides Glycopeptides also inhibit cell wall synthesis by preventing peptidoglycan formation. Vancomycin Indications : IV for Serious GRAM+ve infections – MRSA – septicaemia, endocarditis. Orally for pseudomembranous colitis (c.diff) Route/Dose: 1-1.5g bd ivi (slowly – risk of anaphylaxis) 125mg qds po. Side effects : Nephrotoxicity Ototoxicity (stop if get tinnitus) Rash Hypersensitivity. Caution: History of deafness IBD (increased bowel uptake if given PO) Interactions: Ciclosporin – increased nephrotoxicity
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Unformatted text preview: Loop diuretics increased ototoxicity. Monitor: Serum levels FBC and U&E Auditory function. Teicoplanin Indications: Serious GRAM +ve infections MRSA Route/Dose: 400mg im/iv loading dose then reduce to 200mg od Side effects: GI upset Hypersensitivity reaction Ototoxic Nephrotoxic (less than vancomycin) Caution: Breast feeding Pregnancy Renal or hepatic failure. Monitor: FBC U&E LFTs Auditory function....
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Antibiotics Glycopeptides - Loop diuretics increased...

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