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Unformatted text preview: ..(warn patient on long term therapy to watch for fever, sore throat, rash, mouth ulcers, bleeding or bruising) Caution: Low folate Breast feeding Pregnancy Renal failure or in elderly. Contraindicated: Blood disorders megaloblastic anaemia Interactions: Increases effects of warfarin and phenytoin Increased risk of arrhythmias if on amiodarone. Others Nitrofurantoin used in UTIs. SE's include lung effusions and fibrosis. Can give false +ve on urine dipstick for glucose and discolour urine. used topically to treat bacterial conjuntivitis and oral/IV for typhoid fever/h.influenzae meningitis . SE's include bone marrow aplasia are usually fatal. Linezolid newer drug. Active against MRSA and vancomycin resistant enterococcci. Adverse effects include peripheral neuropathy and bone marrow suppression....
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- Fall '10