Antibody functions

Antibody functions - Antibody functions : antibodies bind...

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Unformatted text preview: Antibody functions : antibodies bind to antigens to form antigen-antibody complexes that inactivate antigens or target them for destruction o Precipitation : large antigen-antibody complexes formed that settle out of solution; makes easier targets for macrophages o Lysis : antibodies bind to antigens on surface of bacteria & mismatched red blood cells; complement binding site of antibody binds complement, which triggers complement fixation & cell death o Agglutination : IgM binds to antigens on surface of mismatched red blood cells & forms large complexes (clumping) o Neutralization : antibody binds to active site of toxin (from virus or bacteria) & inactivates it o Monoclonal antibodies : pure antibody preparations produced from a B cell clone used in clinical applications Cell-mediated immune response : T cells stimulated by antigen; leads to lysis of virusinfected cells or cancer cells &/or elevation of immune response- Clonal selection of T cells: immunocompetent but nave T cell is activated by...
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Antibody functions - Antibody functions : antibodies bind...

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