This preview shows pages 1–2. Sign up to view the full content.
This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: Antibody functions : antibodies bind to antigens to form antigen-antibody complexes that inactivate antigens or target them for destruction o Precipitation : large antigen-antibody complexes formed that settle out of solution; makes easier targets for macrophages o Lysis : antibodies bind to antigens on surface of bacteria & mismatched red blood cells; complement binding site of antibody binds complement, which triggers complement fixation & cell death o Agglutination : IgM binds to antigens on surface of mismatched red blood cells & forms large complexes (clumping) o Neutralization : antibody binds to active site of toxin (from virus or bacteria) & inactivates it o Monoclonal antibodies : pure antibody preparations produced from a B cell clone used in clinical applications Cell-mediated immune response : T cells stimulated by antigen; leads to lysis of virusinfected cells or cancer cells &/or elevation of immune response- Clonal selection of T cells: immunocompetent but nave T cell is activated by...
View Full Document
- Fall '10