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Autoimmunity Systemic lupus erythematosus

Autoimmunity Systemic lupus erythematosus - Autoimmunity...

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Autoimmunity Systemic lupus erythematosus SLE is a chronic autoimmune disease that can be fatal, although with recent medical advances, fatalities are becoming increasingly rare. As occurs in other autoimmune diseases, the immune system attacks the body’s cells and tissue, resulting in inflammation and tissue damage. SLE can affect any part of the body, but most often harms the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system. The course of the disease is unpredictable, with periods of illness alternating with remissions. Lupus can occur at any age, and is most common in women, particularly of non-European descent; 90% of people diagnosed with SLE are women. Lupus is treatable through addressing its symptoms, mainly with corticosteroids and immunosuppressant’s; there is currently no cure. Survival in patients with SLE in the United States, Canada, and Europe is approximately 95% at five years, 90% at 10 years, and 78% at 20 years.
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