Bacteria and parasites Pathogenic bacteria

Bacteria and parasites Pathogenic bacteria - Bacteria and...

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Bacteria and parasites Pathogenic bacteria Pathogenic bacteria: reasons for disease The bacterial factors which confer pathogenicity on bacteria are referred to as pathogenicity factors (aka virulence factors) These are sometimes encoded by plasmids which may spread from pathogenic to non- pathogenic bacterial strains Bacteria seeks to invade host Host seeks to destroy bacteria Both these processes – invasion and resistance – cause symptoms of disease either by direct damage or by inflammation Infection with pathogenic bacteria does not necessarily result in disease o e.g. less than 30% of those drinking water contaminated with Vibrio cholerae develop cholera o A 19 th century physician Max Pettenkofer publicly drank a culture of V. cholerae (he did Hence: Host + pathogen = disease Obviously it is the immune system (innate and adaptive) that determines whether disease develops It follows that host factors related to immunosuppression, e.g. malnutrition, influence whether disease develops. Pathogenic Bacteria
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Bacteria and parasites Pathogenic bacteria - Bacteria and...

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