Capillary beds - o macula densa group of tall closely...

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Capillary beds (Microvasculature) of Nephron o Peritubular capillaries : arise from most efferent arterioles draining glomeruli Vasa recta : in deepest part of cortex, efferent arterioles form bundles of long straight vessels (rather than emptying into peritubular capillaries) serving juxtamedullary nephrons o vascular resistance in microcirculation protects glomeruli from fluctuations in systemic blood pressure - Juxtaglomerular apparatus : region in nephron where initial portion of DCT lies against arteriole feeding glomerulus o Juxtaglomerular (JG) cells : smooth muscle cells with secretory granules containing renin Act as mechanoreceptors to sense blood pressure in afferent arteriole
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Unformatted text preview: o macula densa : group of tall, closely packed DCT cells that lies adjacent to JG cells act as chemoreceptors (or osmoreceptors) that respond to changes in solute content o mesangial cells : appear to play a role in controlling rate of filtration- Filtration membrane : filter that lies between blood & interior of glomerular capsule; consists of: o fenestrated endothelium of glomerular capillaries: allows all plasma components but not blood cells to pass Kevin Kelleher, MTC Biology 211 Study Notes Exam 3 18 o visceral membrane of glomerular capsule (made of podocytes) o Intervening basement membrane composed of fused basal laminas of other layers: restricts large proteins but allow small proteins & solutes to pass PAGE2...
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