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Chronic renal failure

Chronic renal failure - progression to stage 5 While renal...

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Chronic renal failure Treatment The goal of therapy is to slow down or halt the progression of CKD to stage 5. Control of blood pressure and treatment of the original disease, whenever feasible, are the broad principles of management. o Lifestyle advice – exercise, salt restriction, give statins regardless of lipid levels o BP control – ACEI/ARA, aim for BP <140/85 / Loop diuretics for oedema o Osteodystrophy – calcichew/vitD analogues (alfacalcidol) o Dialysis o Transplantation Prognosis The prognosis of patients with chronic kidney disease is guarded as epidemiological data has shown that all cause mortality (the overall death rate) increases as kidney function decreases. The leading cause of death in patients with chronic kidney disease is cardiovascular disease, regardless of whether there is
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Unformatted text preview: progression to stage 5. While renal replacement therapies can maintain patients indefinitely and prolong life, the quality of life is severely affected. Renal transplantation increases the survival of patients with stage 5 CKD significantly when compared to other therapeutic options; however, it is associated with an increased short-term mortality (due to complications of the surgery). Transplantation aside, high intensity home hemodialysis appears to be associated with improved survival and a greater quality of life, when compared to the conventional three times a week hemodialysis and peritoneal dialysis. Prevention Preventing CRF is about preventing the underlying causes and if they occur making sure they are adequately treated....
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