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Unformatted text preview: following childbirth o milk collects in lactiferous sinuses & is passed into lactiferous ducts , which open to the outside of the nipple o invasive breast cancer is the most common cancer of U.S. women cancer usually arises from epithelial cells of ducts known risk factors include: early onset menses & late menopause; no pregnancies or first pregnancy later in life; previous history of breast cancer; family history of breast cancer (possible risk factors include overexposure to estrogens, cigarette smoking & alcoholism) hereditary forms (~ 10% of all cases) often stem from mutations in breast cancer susceptibility genes BRCA1 & BRCA2 can be detected by breast self-examination & mammography treatment includes radiation & chemotherapy, and surgery (radical mastectomy has been mostly replaced by lumpectomy or, if necessary, simple mastectomy) page7...
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- Fall '10