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Unformatted text preview: Glandular fever Epidemiology Epstein-Barr virus is a DNA-carrying herpes virus and as such produces latent and active infections. Infection is common in young children and is usually mild or asymptomatic. Glandular fever is most likely to produce symptoms in the age group 15-25. Antibody studies show that approximately 50% of adolescents have been exposed to EBV, whilst 75% of over 25s and almost 90% of adults have been exposed. Diagnosis Diagnosis depends upon the combination of clinical symptoms/findings and investigation results. Clinical findings that indicate Glandular fever include:- Cervical lymphadenopathy Sore throat with phalangeal inflammation Systemic features such as fatigue, malaise and fever The following investigations aid diagnosis:- FBC Raised White Cell Count (especially monocytes and lymphocytes) LFTs a rare complication of Glandular Fever is hepatitis which can be detected via abnormal LFTs Paul Bunnell test an antibody test directed at EBV (often not positive until week two of the...
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- Fall '10
- Anthropology, infectious mononucleosis, Cytomegalovirus, glandular fever