Glomerulonephritis Epidemiology

Glomerulonephritis Epidemiology - pressure and again may...

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Glomerulonephritis Epidemiology Glomerulonephritis represents 10-15% of glomerular diseases. Variable incidence has been reported due to the subclinical nature of the disease in more 50% of cases. Despite sporadic outbreaks, incidence of post-streptococcal glomerulonephritis has fallen over the last few decades. Factors responsible for this decline may include better health care delivery and improved socioeconomic conditions. IgA nephropathy glomerulonephritis is the most common cause of glomerulonephritis worldwide. Minimal Change Glomerulonephritis is the commonest cause of glomerulonephritis in children and account for 80% of cases. It has been reported that men are affected more than women at a rate of 2:1. Diagnosis Because symptoms develop gradually, the disorder may only be discovered when there is an abnormal urinalysis during examination for unrelated disorders. Glomerulonephritis can also cause high blood
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Unformatted text preview: pressure, and again may only be discovered if the hypertension proved difficult to treat. If the disease is allowed to progress undiagnosed signs of chronic kidney failure may be seen, including oedema, polyneuropathy, and signs of fluid overload, including abnormal heart and lung sounds. The following investigations can help diagnose Glomerulonephritis:-• Urine output • Urinanalysis (looking at protein levels, creatinine clearance, RBC) • Blood tests including:-o FBC – may reveal anaemia o U&Es – looking for uraemia and electrolyte disturbance o LFTs – may reveal hypoalbuminemia o Immune markers IgA GBM antibodies Anti-neutrophil cytoplasmic antibodies (ANCAs) Compliment and C3 o BUN and creatinine • Imaging o Renal Ultrasound o Chest X-ray • Biopsy (will aid diagnosis immensely)...
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Glomerulonephritis Epidemiology - pressure and again may...

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