Gout1 - intermittent attacks and will benefit from taking...

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Gout Epidemiology Gout affects around 1–2% of the Western population at some point in their lifetime. Rates of gout have approximately doubled between 1990 and 2010. Historically it affected more affluent societies but it now affects all social demographic groups. In men over the age of 30 and women over the age of 50, prevalence is 2%. Prognosis Without treatment, an acute attack of gout will usually resolve in 5 to 7 days. However, 60% of people will have a second attack within one year. Those with gout are at increased risk of hypertension, diabetes mellitus, metabolic syndrome, and renal and cardiovascular disease and thus at increased risk of death. This may be partly due to its association with insulin resistance and obesity, but some of the increased risk appears to be independent Prevention An elevated uric acid level alone is not an indication for long term drug treatment. The vast majority of patients with raised uric acid levels (90%) will remain asymptomatic for life. Some will only suffer
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Unformatted text preview: intermittent attacks and will benefit from taking high-dose NSAIDs and following preventative advice, rather than life-long preventative medication. High-purine foods and dehydration should be avoided. Diuretics and long term low dose aspirin should be prescribed cautiously in individuals who have a past medical history of gout or hyperuricemia. Drug prevention should be aimed at those at risk of long term complications, such as arthritis and chronic renal disease. Those patients most at risk are young patients with high levels of uric acid. is one drug used to prevent gout. It is very effective and safe even when taken long term. Some patients suffer from rashes, but these improve when the drug is withdrawn. inhibits the enzyme xanthine oxidase, which converts xanthine into uric acid. Other preventative drugs include:- Probenecid Sulphinpyrazone...
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This note was uploaded on 12/04/2011 for the course ANTHRO 2000 taught by Professor Monicaoyola during the Fall '10 term at Broward College.

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Gout1 - intermittent attacks and will benefit from taking...

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