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Unformatted text preview: Haemochromotosis Haemochromatosis is a chronic and often silent disorder that results from inappropriate levels of iron in the blood and tissues. Symptoms Haemochromatosis may be silent for many years before a patient seeks medical attention, due to the sub-acute presentation of the disorder. It classically presents in the 4 th-5 th decade of life with non-specific symptoms, such as fatigue, lethargy or muscle pain. They may also present with systemic symptoms such as impotence, diabetes, liver cirrhosis, cardiomyopathy or skin hyperpigmentation. Causes Haemochromatosis is classically thought to be a genetic disease of autosomal recessive inheritance. However, the genetic penetrance of the disorder is unknown since a number of people that carry the most common genetic mutation (the C282Y mutation) do not manifest the disorder. The clinical presentation of the disorder is due to the increased dietary iron absorption and/or increased iron release from cell; leading to inappropriate levels of iron into organs and tissues. Foods that are high iron release from cell; leading to inappropriate levels of iron into organs and tissues....
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This note was uploaded on 12/04/2011 for the course ANTHRO 2000 taught by Professor Monicaoyola during the Fall '10 term at Broward College.
- Fall '10