How the immune system functions Effector mechanisms

How the immune system functions Effector mechanisms - How...

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How the immune system functions Effector mechanisms Mechanisms depend on whether it the pathogen is intracellular (e.g. viruses, some bacteria) or Effector Mechanisms can be broken down into two categories; cell mediated immunity (CMI) antibody mediated or humoral immunity In both cases, the innate and adaptive immune systems co-operate. Cytokines are important in both systems. Cell Mediated Immunity Main mechanisms are: Inflammation Cell-mediated cytotoxicity against virus infected cells mediated by Tc-Cell and NK cells Macrophage activation Inflammation is precipitated by tissue damage (burns, cuts etc.) and by microbes triggering innate immunity. Its role is to signal to the immune system that there is a problem, and to initiate containment of that problem by activating innate immunity. In inflammation: Local cells e.g. epithelial cells will produce cytokines In particular Interleukin-1, TNF and chemokines (a class of cytokine which act as chemo
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How the immune system functions Effector mechanisms - How...

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