Immunodeficiency and malignancies Haematopoietic malignancies

Immunodeficiency and malignancies Haematopoietic malignancies

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Immunodeficiency and malignancies Haematopoietic malignancies These are a very diverse group of diseases affecting the immune system o Underlying defect is uncontrolled proliferation of a lymphoid or myeloid precursor OR a more mature cell including plasma cells o Never the CD34 stem cell o Lead to defects in the immune system (but this is usually not the patients main problem) Nomenclature: conventionally divided into o Leukaemia Cells proliferate in the marrow & spill over into the circulation (hence leuk | aemia); o Lymphoma Cells proliferate in lymph nodes which swell (hence lymphoma), not present in circulation o Myeloma Cells proliferate in bone marrow (myel | oma), not present in circulation. Nomenclature: then named for the specific cell type involved: o E.g. B cell lymphoma (many different kinds), affecting mature B cells; o E.g. Acute myeloid (myelogenous) leukaemia (AML) affecting pre-granulocyte/monocyte cells....
View Full Document

Page1 / 4

Immunodeficiency and malignancies Haematopoietic malignancies

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online