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Unformatted text preview: of influenza are:- Neuraminidase inhibitors o Neuraminidase inhibitors that are designed to halt the spread of the virus in the body o These drugs are often effective against both influenza A and B o Examples include:- Oseltamivir Zanamivir M2 inhibitors (adamantanes) o M2 inhibitors block a viral ion channel (M2 protein) and prevent the virus from infecting cells o These drugs are sometimes effective against influenza A if given early in the infection but are always ineffective against influenza B because B viruses do not possess M2 molecules o Measured resistance to M2 inhibitors in isolates of H3N2 has increased to 91% in 2005 o Examples include:- Amantadine Rimantadine...
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- Fall '10