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Interstitial nephriti1 - Interstitial nephritis...

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Interstitial nephritis Interstitial nephritis (or tubulointerstitial nephritis) is a form of nephritis that affects the parenchyma around the nephrons. Symptoms Interstitial nephritis can cause mild to severe renal problems, including acute kidney failure. In approximately 50% of cases, patients will have decreased urine output and other signs of acute kidney failure, which include:- Haematuria Fever Increased or decreased urine output Uraemia leading to:- o Nausea and vomiting o Lethargy o Confusion o Coma Rash Oedema Arthralgia Causes Interstitial nephritis may be temporary or it may be long lasting and get worse over time. Commoner causes include: - Allergic reactions to drugs o Antibiotics Cephalosporins, Penicillins, Sulphonamides, Rifampicin o Diuretics Furosemide, Thiazides o Others Allopurinol, Cimetidine
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Analgesics o Non-steroidal anti-inflammatory drugs (NSAIDs) o Paracetamol Infections o Staphylococci o Streptococci o Brucella
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