{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Klinefelte1 - • Decreased libido Causes Klinefelter’s...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Klinefelter's syndrome Klinefelter's syndrome is a genetic condition in which men inherit an additional X chromosome leading to 47 XXY males Symptoms The onset of symptoms produced by this chromosomal disorder vary and in a few cases go unnoticed. If the symptoms of Klinefelter's do become apparent, they tend to do so around puberty or early adulthood and include:- Tall stature, slight build and long slender limbs Gynaecomastia Female adipose tissue distribution (hips and gluteal region) Microorchidism +/- Micropenis Sparse facial and body hair Mild educational difficulties Infertility – due to impaired Seminiferous tubular function
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: • Decreased libido Causes Klinefelter’s is caused by the presence of an additional X chromosome, however in rare cases in can be caused by up to three extra X chromosomes (XXXXY). Males with Klinefelter syndrome may have a mosaic 47 XXY/46 XY constitutional karyotype and varying degrees of spermatogenic failure. Mosaicism 47 XXY/46 XX with clinical features suggestive of Klinefelter syndrome is very rare. Thus far, only about 10 cases have been described in literature. The cause for additional X Chromosomes remains unclear; however it is observed that the incidence is found to be higher in children of elderly mothers....
View Full Document

{[ snackBarMessage ]}

Ask a homework question - tutors are online