Klinefelte1 - Decreased libido Causes Klinefelters is...

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Klinefelter's syndrome Klinefelter's syndrome is a genetic condition in which men inherit an additional X chromosome leading to 47 XXY males Symptoms The onset of symptoms produced by this chromosomal disorder vary and in a few cases go unnoticed. If the symptoms of Klinefelter's do become apparent, they tend to do so around puberty or early adulthood and include:- Tall stature, slight build and long slender limbs Gynaecomastia Female adipose tissue distribution (hips and gluteal region) Microorchidism +/- Micropenis Sparse facial and body hair Mild educational difficulties Infertility – due to impaired Seminiferous tubular function
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Unformatted text preview: Decreased libido Causes Klinefelters is caused by the presence of an additional X chromosome, however in rare cases in can be caused by up to three extra X chromosomes (XXXXY). Males with Klinefelter syndrome may have a mosaic 47 XXY/46 XY constitutional karyotype and varying degrees of spermatogenic failure. Mosaicism 47 XXY/46 XX with clinical features suggestive of Klinefelter syndrome is very rare. Thus far, only about 10 cases have been described in literature. The cause for additional X Chromosomes remains unclear; however it is observed that the incidence is found to be higher in children of elderly mothers....
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This note was uploaded on 12/04/2011 for the course ANTHRO 2000 taught by Professor Monicaoyola during the Fall '10 term at Broward College.

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